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引用本文:陈洁君. 高等级病原微生物实验室建设科技进展[J]. 生物安全学报, 2018, 27(2): 80-87.
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高等级病原微生物实验室建设科技进展
陈洁君
中国生物技术发展中心, 北京 100039
摘要:
高等级病原微生物实验室是生物安全级别最高的防护实验室,是从事高致病性病原微生物检测和科学研究的重要技术平台,也是保护实验室工作人员不被感染、外界环境不受污染的防护屏障。近年来,强致病性微生物引发的烈性传染病在全球范围内逐步扩散。世界各国为满足应急控制传染病突发事件以及提升生物国防实力的重大需求,纷纷开始加紧建设高等级病原微生物实验室。阐述了世界生物安全实验室的发展历程与等级划分,各国高等级病原微生物实验室的建设进展与成果以及我国高等级病原微生物实验室在关键技术、装备研发以及国产化四级模式实验室建设等方面所取得的科技进展,并对未来科技发展方向进行了展望。
关键词:  高等级病原微生物实验室  建设  分级  科技进展
DOI:10.3969/j.issn.2095-1787.2018.02.002
基金项目:
附件
Progress in the construction of the high-grade pathogenic microbiology laboratory
CHEN Jiejun
China National Center for Biotechnology Development, Beijing 100039, China
Abstract:
The high-grade pathogenic microbiological laboratory is the highest level of biosafety protection (level Ⅳ), as well as an important technical platform for the detection and scientific research of highly pathogenic microorganisms. It is also a barrier to protect staff working in the laboratory and the external environment from infection and pollution. Recently, severe infectious diseases caused by strongly pathogenic microorganisms spread throughout the world. In order to satisfy all major biological defense demands, various countries have started to intensify efforts to build high biosafety level laboratoreis for the study of dengerously pathogenic microbes. This article is an overview of the scientific progress of high-grade pathogenic microbiology laboratories in key technologies, equipment development, as well as the construction of national level Ⅳ laboratory in China.
Key words:  high-grade pathogenic microbiology laboratory  establish  classfication  technological advance